By Dr. Ross Feldman,
Medical Lead,
Cardiac Sciences Manitoba

November 17, 2019

CSP News

The results of the ISCHEMIA study presented yesterday at the AHA should reinforce our appreciation that atherosclerosis is a systemic disease– and the principal therapies should be systemic, not local (Medscape commentary link appended Thus, while we are often focused on identification of the optimal form of revascularization for patients with advanced coronary artery disease, my first impression of the ISCHEMIA results (much like the learnings from COURAGE study before it and similar to the evolution of our understanding of the lack of a role of revascularization for renal artery stenosis) is that that focus should, for many patients, remain with risk reduction. I look forward to further discussion as the details of this study become more widely available.

A few words about statistical support from CSP

The CSP has had a long tradition of ad hoc statistical support for a range of research projects across the community. This has been an important resource for many students and scientists. Our current local support (aka Brett) has been stretched by the increased demands by CSP as we transform towards a provincial mandate as well as his “double-duty roles” because of recent retirements/relocations. We are endeavoring to recapitulate that statistical support resource through the restructuring of the CHaRM program– on a “partial cost recovery basis”. However, currently we don’t have the capacity to handle statistical requests that we did.

In the interim, from what I understand, there are the following resources currently available at the University of Manitoba and elsewhere for statistical support on medical research projects. I am sure there are others, however these are the ones we are currently aware of:

The George and Fay Yee Centre for Healthcare Innovation provides fee-for-service support to various research projects, and have several trained biostatisticians available to work on a variety of medical research projects (both Basic Sciences and Clinical Research).

In addition, the Department of Internal Medicine has a full time statistician available for use to the Cardiology section.

For projects initiated at the Manitoba Centre for Health Policy, they can also provide statistical support for all required analysis for a given project.

The Department of Statistics at the University of Manitoba also provide consultation services

We are working at re-establishing a robust process for onsite statistical support. Thanks for your patience as we work through the details.

Shout Outs!

Happy Nurse Practitioners Week to all the NP’s within our program. Thank you for your dedication and hard work you put in daily to ensure our patients receive excellent care!

Please join us on Wednesday November 20, 2019 at 4:00 PM in the Sam Cohen Auditorium, Albrechtsen Research Centre for the Cardiac Sciences Program’s first monthly Visiting Professor Series Lecture for this academic year. This month’s guest is Dr. Raj Padwal. His talk will take place a 4:00 PM titled “Hypertension: The Forgotten Risk Factor” followed by a reception in the Atrium. Hope to see you there!

Publications by our Faculty this Week

Ma B, Allen DW, Graham MM, Har BJ, Tyrrell B, Tan Z, Spertus JA, Brown JR, Matheny ME, Hemmelgarn BR, Pannu N, James MT. Comparative Performance of Prediction Models for Contrast-Associated Acute Kidney Injury After Percutaneous Coronary Intervention. Circ Cardiovasc Qual Outcomes. 2019 Nov;12(11):e005854. doi: 10.1161/CIRCOUTCOMES.119.005854. Epub 2019 Nov 14.

Kwok CS, Zieroth S, Van Spall HGC, Helliwell T, Clarson L, Mohamed M, Mallen C, Duckett S, Mamas MA. The Hospital Frailty Risk Score and its association with in-hospital mortality, cost, length of stay and discharge location in patients with heart failure short running title: Frailty and outcomes in heart failure. Int J Cardiol. 2019 Oct 9. pii: S0167-5273(19)32961-4. doi: 10.1016/j.ijcard.2019.09.064. [Epub ahead of print]